Table 4.
Comparisons of the estimates from the mixture terminal (or cure) rate model and the RMTI based on the reconstructed data from the second figure in Wang et al [13].
| Terminal rate model | Remdesivir | Placebo | Difference | P Value | Hazard ratio (95% CI) | P value | |
| Terminal rate, % (95% CI) | 0.31 (0.27-0.37) | 0.41 (0.32-0.51) | –9.22 (–22.9 to 4.45) | .19 | 0.92 (0.63-1.35) | .67 | |
| RMTIa | |||||||
|
|
Day 7 | 6.95 (6.90-7.00) | 6.97 (6.92-7.00) | –0.03 (–0.10 to 0.05) | .49 | N/Ab | N/A |
|
|
Day 14 | 13.09 (12.78-13.40) | 13.29 (12.92-13.67) | –0.20 (–0.69 to 0.29) | .42 | N/A | N/A |
|
|
Day 28 | 20.42 (19.26-21.57) | 21.31 (19.73-22.88) | –0.89 (–2.84 to 1.06) | .37 | N/A | N/A |
aRMTI: restricted mean time to improvement.
bNot applicable.