. 2020 Jun 30;14(6):e0008375. doi: 10.1371/journal.pntd.0008375

Table 6. Distribution of Escherichia coli pathotypes and virulence genes among cases and controls.

Pathotype (n)^a	Subtypes	Genes	Cases		Controls
Pathotype (n)^a	Subtypes	Genes	n	%	n	%
ETEC (27)	ST-ETEC	st	7	41.2	0	-
	nonST-ETEC	lt	5	29.4	10	100
	ST-ETEC	st, lt	5	29.4	0	-
EAEC (115)^a	Typical EAEC	aggR with or without aaiC	38	65.5	38	66.7
EAEC (115)^a	Atypical EAEC	aaiC, with negative aggR	20	34.5	19	33.3
EPEC (82)	Atypical EPEC	eae^b	29	93.5	47	92.2
EPEC (82)	Typical EPEC	eae, bfpA^c	2	6.5	4	7.8
DAEC (6)		daaE	4	100	2	100
EIEC (3)		ipaH, ipaD	1	100	2	100
STEC (3)		eae, stx1 and/or stx2	3	100	0	-
Emergent E. coli pathotypes	EAEC/ETEC (1)	aggR, aaiC, st	1	25	0	-
	EAEC/EPEC (1)	aggR, aaiC, eae, bfpA	1	25	0	-
	BF-EIEC (2)	ipaH, ipaD, O96:H19^d	2	50	0	-

^aThe total number of subjects positive for EAEC were 115, however the total number of typical EAEC and atypical EAEC was 122 because both typical and atypical EAEC were detect in the stool of a total of 5 subjects;

^b eae: this genotype corresponds to atypical ETEC;

^ceae, bfpA genotype corresponds to typical EPEC;

^d BF-EIEC is an emergent EIEC strain with unusual serotype.

Abbreviations: ETEC: Enterotoxigenic E. coli; ST-ETEC: Heat stable toxin ETEC; EAEC: Enteroaggregative E. coli; EPEC: Enteropathogenic E. coli; EIEC: Enteroinvasive E. coli; and STEC: Shiga toxin-producing E. coli; DAEC: Diffusely adherent E. coli; BF-EIEC: Biofilm-forming enteroinvasive E. coli.