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. 2019 Nov 2;1:1–10. doi: 10.1016/j.crphys.2019.10.001

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© 2019 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Fig. 1 — Echocardiography analysis in different age groups after 2-week TAC and sham surgery. (A) Example echocardiography of left ventricle. (B) Left ventricular relative wall thickness (RWT). (C) Left ventricular end-diastolic internal dimension (LVEDD). (D) Left ventricular end-systolic internal dimension (LVESD). (E) Left ventricular fractional shortening (FS). (F) In C57BL/6N TAC mice, FS decreased in an age dependent manner (R² = 0.430, p = 0.003). Data are shown as means ± SE (n = 8 for sham and n = 6–14 per group for TAC). *P < 0.05 compared with the sham group of same strain, showing significant increase; §P < 0.05 compared with the sham group of same strain, showing significant decrease; #P < 0.05 compared with C57BL/6J mice of the same age group.