Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Heart failure rate in mice aged 8 weeks after 2-week and 5-week TAC.
| TAC duration (week) | C57BL/6J | C57BL/6N | P value |
|---|---|---|---|
| 2 | 20% (2/10) | 25% (3/12) | 1.000 |
| 5 | 25% (2/8) | 100% (5/5) | 0.021 |
| P value | 1.000 | 0.009 |
Heart failure with reduced systolic function was defined as having dyspnea, body weight loss (approximately 10% decrease), increased wet lung weight and reduced fractional shortening on echocardiography compared with sham controls.
