Table 3.
Conscious electrocardiography before and after 2-week TAC in C57BL/6J and C57BL/6N mice.
| C57BL/6J |
C57BL/6N |
P (BL/6J vs. BL/6N TAC) | |||||
|---|---|---|---|---|---|---|---|
| Sham | 2-week TAC | P | Sham | 2-week TAC | P | ||
| N number | 11 | 6 | 7 | 9 | |||
| Heart rate, bpm | 748 ± 12 | 759 ± 8 | NS | 735 ± 15 | 764 ± 12 | NS | NS |
| RR interval, ms | 80.3 ± 1.3 | 79.1 ± 0.8 | NS | 81.6 ± 1.7 | 78.7 ± 1.2 | NS | NS |
| PR interval, ms | 32.3 ± 0.7 | 33.0 ± 0.7 | NS | 31.5 ± 0.9 | 31.3 ± 1.2 | NS | NS |
| P duration, ms | 7.77 ± 0.60 | 8.95 ± 0.63 | NS | 6.45 ± 0.31 | 9.26 ± 0.33 | 0.000 | NS |
| QRS interval, ms | 10.4 ± 0.5 | 16.0 ± 0.5 | 0.000 | 12.2 ± 0.4 | 19.4 ± 1.3 | 0.000 | 0.009 |
| QT interval, ms | 22.9 ± 2.0 | 30.4 ± 0.7 | 0.006 | 24.8 ± 0.7 | 34.6 ± 1.8 | 0.000 | 0.045 |
| QTc, ms | 81.2 ± 7.2 | 108.0 ± 2.9 | 0.003 | 85.1 ± 2.2 | 124.3 ± 6.4 | 0.000 | 0.036 |
| JT interval, ms | 12.6 ± 1.5 | 14.4 ± 0.5 | NS | 12.7 ± 0.5 | 15.5 ± 0.9 | 0.038 | NS |
Measurements are represented as mean ± SE and compared with 2-tailed Student's t-test. TAC, transverse aortic constriction; NS, not significant.