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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Exp Neurol. 2019 Dec 12;325:113146. doi: 10.1016/j.expneurol.2019.113146

Figure 3. ROR-γ inhibition in patients with MG reduces Th17 cell frequencies but does not affect other Th cell subsets.

Figure 3.

A) ROR-γ inhibition in MG patients produced a strong trend towards reduced frequencies of Th17 cells (CD4+IL-17+; n=34), but not B) Tregs (CD4+ FOXP3+, n=35), C) Th1 (CD4+ IFN-γ+, n=35), D) Th2 (CD4+IL-4+, n=27), E) Tfh (CD4+CXCR5, n=33), or F) CD4+IL-21+ (n=35) T cells subsets. Statistical significance is represented as follows: * p≤0.05.