Table 2. Top 35 differentially expressed genes in the Mac II cluster.
ScRNA-Seq was performed on live CD45+ lung cells isolated from E18.5, P1, P7 and P21 B6 pups. Top 35 upregulated genes are shown for the Mac II cluster; n = 2 mice.
| Mac II cluster top 35 differentially expressed genes | |||
|---|---|---|---|
| Gene name | Statistic | P value | Log2 fold change |
| Adgrl3 | 0.5713 | 8.85E-42 | 3.8593 |
| Adarb1 | 0.4216 | 5.92E-23 | 2.6952 |
| Ms4a8a | 0.4528 | 2.11E-26 | 2.4485 |
| Nav2 | 0.4751 | 4.97E-29 | 2.1319 |
| Tmcc3 | 0.4289 | 9.85E-24 | 2.0579 |
| Ldhb | 0.3809 | 8.26E-19 | 2.0235 |
| Acp5 | 0.3837 | 4.45E-19 | 2.0198 |
| Dapk1 | 0.3658 | 2.20E-17 | 1.8704 |
| Itgax | 0.5825 | 2.02E-43 | 1.8680 |
| Csf2rb2 | 0.3459 | 1.11E-16 | 1.7791 |
| H2-DMa | 0.5022 | 2.22E-32 | 1.7642 |
| Trerf1 | 0.3850 | 3.31E-19 | 1.7402 |
| Dmxl2 | 0.4117 | 6.59E-22 | 1.7264 |
| Tgm2 | 0.3663 | 1.99E-17 | 1.6906 |
| Ear2 | 0.5159 | 3.79E-34 | 1.6602 |
| Dok2 | 0.3695 | 1.00E-17 | 1.6373 |
| Flt1 | 0.3655 | 2.34E-17 | 1.5457 |
| Axl | 0.5068 | 5.74E-33 | 1.4698 |
| AU020206 | 0.3723 | 5.40E-18 | 1.4207 |
| Ece1 | 0.3962 | 2.54E-20 | 1.4075 |
| Ear10 | 0.3938 | 4.41E-20 | 1.4069 |
| Il18 | 0.4084 | 1.46E-21 | 1.4021 |
| Clec7a | 0.4959 | 1.37E-31 | 1.3413 |
| Spint1 | 0.3724 | 5.29E-18 | 1.3407 |
| Mpeg1 | 0.5454 | 4.05E-38 | 1.3269 |
| Il1rn | 0.3463 | 1.11E-16 | 1.2922 |
| Clec4n | 0.4454 | 1.45E-25 | 1.2765 |
| Fn1 | 0.4088 | 1.34E-21 | 1.2497 |
| Il1b | 0.4002 | 1.02E-20 | 1.2281 |
| Dst | 0.4484 | 6.72E-26 | 1.1994 |
| F11r | 0.4129 | 4.97E-22 | 1.1982 |
| Nceh1 | 0.3548 | 2.24E-16 | 1.1299 |
| Neurl3 | 0.3721 | 5.74E-18 | 1.1091 |
| Tnfaip2 | 0.3785 | 1.40E-18 | 1.0880 |
| Plet1 | 0.4461 | 1.23E-25 | 1.0845 |