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. Author manuscript; available in PMC: 2021 Jan 15.
Published in final edited form as: Clin Cancer Res. 2020 Jan 14;26(14):3856–3867. doi: 10.1158/1078-0432.CCR-19-1397

Fig 3. Biological impact of AMG-176 in normal PBMCs.

Fig 3.

Normal PBMCs were isolated from peripheral blood sample of healthy donors. PBMCs were cultured in media supplemented with 10% human serum. Each sample was treated with either dimethyl sulfoxide (DMSO) (0.1%) or 300 nM AMG-176 for 24 hours. Cell death was determined using flow cytometry after Annexin V/propidium iodide (PI) staining and cell surface marker staining. A. PBMCs, B. CD19+ B-cells. C. CD4+ T-cells. D. CD8+ T-cells. E. CD56+ NK-cells. F. CD133+ plasma cells and G. CD34+ myeloid cells.