Table 5.

TINCR polymorphisms and their association with cancer risk.

Cancer type	Cases/Control	SNP ID	OR (95%CI)	p-value	Description	Reference
Gastric cancer	602/602	rs8113645	0.70 (0.55–0.89)	0.003	GA and AA genotypes were significantly associated with decreased GC risk. GA + AA genotype carriers had lower TINCR mRNA expression levels compared with common genotype in both normal and GC tissues.	[32]
		rs2288947	0.83 (0.70–0.99)	0.037	AG and GG genotypes were significantly associated with decreased GC risk.
Colorectal cancer	1400/1400 (Stage I: 600, Stage II: 800)	rs2288947	0.77 (0.67–0.88)	1.2 × 10−4	The G allele was associated with 23% decreased risk of colorectal cancer.	[33]
		rs8105637	1.22 (1.09–1.37)	6.2 × 10−4	The A allele was associated with 22% increased risk of colorectal cancer.