Table 2.
List of isolated anti-AAV antibody sequences and corresponding IMGT germline loci.
| Clone ID | Heavy | Kappa | Lambda |
|---|---|---|---|
| 1G4 | 4-59*08 | 3-20*01 | |
| 8F9 | 3-33*03 | 4-1*01 | |
| 3-48*01 | |||
| 4-30-4*01 | |||
| 1-46*01 | |||
| 15G3 | 1-46*01 | 4-1*01 | |
| 21B6 | 3-33*03 | 2-11*01 | |
| 22C8 | 1-18*01 | ||
| 26F4 | 3-49*04 | 2-28*01 | |
| 30D5 | 1-2*02 | 2-14*01 | |
| 31C3 | 4-61*02 | 4-1*01 | |
| 46C11 | 3-48*01 | 1-13*02 | |
| 46D10 | 3-30*02 | 1-5*03 | |
| 46F4 | 4-39*07 | 2-29*02 | |
| 47D11 | 3-30*02 | 3-11*01 | |
| 51B6 | 3-21*03 | 1-40*01 | |
| 53C10* | 3-49*04 | 3-11*01 | 1-47*01 |
| 55B4 | 3-48*01 | 1-5*01 | |
| 65F3 | 3-9*01 | 1-40*01 | |
| 72D3 | 3-30*02 | 3-11*01 | |
| 74E4 | 4-30-4*01 | 3-11*01 | |
| 75B3 | 1-18*01 | ||
| 77B10 | 3-33*03 | 2-11*01 | |
| 4-59*08∧ | |||
| 81C10 | 3-30*02 | ||
| 81G5 | 4-39*01 | 1-40*01 | |
| 86D7 | 3-30*09 | 2-11*01 | |
| 92G6* | 3-9*01 | 1-13*02 (c3) | 2-11*01 |
| 3-30*02∧ | 3-11*01(c9) | ||
| 92G8 | 3-49*04 | ||
| 98C6 | 3-48*01 | 2-14*01 | |
| 99E8 | 4-61*02 | ||
| 100E4 | 3-30*04 | 3-9*01 | |
| 100G3 | 4-61*02 | 3-1*01 |
Underlined clone IDs were produced recombinantly and evaluated in vitro by ELISA and NAb assay. *= all combinations of heavy and light chains were evaluated, ∧= this chain was excluded from evaluation.