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. 2020 Jul 11;6(7):e04377. doi: 10.1016/j.heliyon.2020.e04377

Table 3.

Effect of diabetes mellitus type 2 and its complications on body physiologic parameters.

Control DM DPN DN R2
Systolic BP (mmHg) 119.3 ± 3.74 121.1 ± 3.22 138.7 ± 3.27aaa,bb 131.3 ± 2.85 0.1646
Diastolic BP (mmHg) 74.7 ± 1.93 78.06 ± 1.94 84.13 ± 2.03aa 84.59 ± 1.67aa 0.1339
HbA1C (%) 4.48 ± 0.078 6.87 ± 0.435aaa 8.87 ± 0.439aaa,bb 9.45 ± 0.502aaa,bbb 0.4496
Fasting plasma glucose (mmol/l) 4.62 ± 0.11 8.13 ± 0.37aaa 10.27 ± 0.46aaa,bb 11.64 ± 0.59aaa,bbb 0.5778
Fasting Insulin (pmol/l) 31.76 ± 1.93 111.2 ± 6.52aaa 141.6 ± 10.44aaa,b 104 ± 7.9aaa,cc 0.5074
Vibration perception threshold (Volt)< 9.31 ± 1.541 14.36 ± 1.541a 32.25 ± 1.51aaa,bbb 41.75 ± 1.34aaa,bbb,ccc 0.7802

Data expressed are means ± SEM, n = 30 after Shapiro Wilk normality test has been performed. Data were analyzed by two-way ANOVA followed by Tukey's multiple post hoc test. a,b,c p < 0.05 vs control, DM group and DNP group respectively. Key: Diabetic without neuropathy (DM); Diabetic painful neuropathy (DNP); Diabetic neuropathy without pain (DN); Eta squared (R2); Blood Pressure (BP).