Table 3.
Effect of diabetes mellitus type 2 and its complications on body physiologic parameters.
Control | DM | DPN | DN | R2 | |
---|---|---|---|---|---|
Systolic BP (mmHg) | 119.3 ± 3.74 | 121.1 ± 3.22 | 138.7 ± 3.27aaa,bb | 131.3 ± 2.85 | 0.1646 |
Diastolic BP (mmHg) | 74.7 ± 1.93 | 78.06 ± 1.94 | 84.13 ± 2.03aa | 84.59 ± 1.67aa | 0.1339 |
HbA1C (%) | 4.48 ± 0.078 | 6.87 ± 0.435aaa | 8.87 ± 0.439aaa,bb | 9.45 ± 0.502aaa,bbb | 0.4496 |
Fasting plasma glucose (mmol/l) | 4.62 ± 0.11 | 8.13 ± 0.37aaa | 10.27 ± 0.46aaa,bb | 11.64 ± 0.59aaa,bbb | 0.5778 |
Fasting Insulin (pmol/l) | 31.76 ± 1.93 | 111.2 ± 6.52aaa | 141.6 ± 10.44aaa,b | 104 ± 7.9aaa,cc | 0.5074 |
Vibration perception threshold (Volt)< | 9.31 ± 1.541 | 14.36 ± 1.541a | 32.25 ± 1.51aaa,bbb | 41.75 ± 1.34aaa,bbb,ccc | 0.7802 |
Data expressed are means ± SEM, n = 30 after Shapiro Wilk normality test has been performed. Data were analyzed by two-way ANOVA followed by Tukey's multiple post hoc test. a,b,c p < 0.05 vs control, DM group and DNP group respectively. Key: Diabetic without neuropathy (DM); Diabetic painful neuropathy (DNP); Diabetic neuropathy without pain (DN); Eta squared (R2); Blood Pressure (BP).