Figure 4.
5-HT1B agonist CP 94253 reduces impulsivity. A, DIY-NAMIC boxes allow for continuous assessment of the behavioral effects of pharmacological manipulations on impulsive action. The average number of nosepokes during the 9-s delay window per trial is shown over the 12-h dark phase immediately following injection of vehicle or drug (CP 94253). B, Binned by 6 h, premature responses are shown for the first and second halves of the dark phase following vehicle or drug administration. Other measures including total number of trials initiated (C), ITI responding (D), proportion of omitted trials (E), and proportion of correct attempted trials (F) are shown for drug and saline conditions over first and second half of dark phase.