Table 3.
Cox regression analysis for OS.
| Univariate Analysis | Multivariate Analysis | |||
|---|---|---|---|---|
| HR (95%CI) | P | HR (95%CI) | P | |
| Age ≥70 (vs. <70) | 2.025 (0.846-4.844) | 0.113 | - | - |
| Female (vs. male) | 1.335 (0.599-2.975) | 0.479 | - | - |
| Tobacco use (yes vs. no) | 0.896 (0.406-1.978) | 0.785 | - | - |
| Alcohol use (yes vs. no) | 1.137 (0.532-2.428) | 0.741 | - | - |
| Performance status (1 vs. 0) | 4.901 (0.662-36.278) | 0.120 | - | - |
| NCRT vs. (NCT) | 1.491 (0.623-3.570) | 0.370 | - | - |
| Clinical stage III/IV (vs. II) | 3.580 (1.340-9.567) | 0.011 | 1.901 (0.650-5.562) | 0.241 |
| IDO1-decline vs. IDO1-rise | 0.293 (0.127-0.675) | 0.004 | 0.416 (0.175-0.990) | 0.047 |
| H-ΔCD8 vs. L-ΔCD8 | 2.594 (1.176-5.724) | 0.018 | 1.670 (0.720-3.870) | 0.232 |
| pN staging (N+ vs. N0) | 4.206 (1.836-9.635) | 0.001 | 3.275 (1.383-7.756) | 0.007 |