Table 4.
Cox regression analysis for DFS.
| Univariate Analysis | Multivariate Analysis | |||
|---|---|---|---|---|
| HR (95%CI) | P | HR (95%CI) | P | |
| Age ≥70 (vs. <70) | 1.408 (0.642-3.089) | 0.393 | - | - |
| Female (vs. male) | 0.924 (0.448-1.905) | 0.830 | - | - |
| Tobacco use (yes vs. no) | 1.034 (0.538-1.985) | 0.921 | - | - |
| Alcohol use (yes vs. no) | 1.179 (0.623-2.233) | 0.613 | - | - |
| Performance status (1 vs. 0) | 2.150 (0.659-7.014) | 0.204 | - | - |
| NCRT vs. (NCT) | 1.613 (0.762-3.415) | 0.211 | - | - |
| Clinical stage III/IV (vs. II) | 2.264 (1.092-4.692) | 0.028 | 1.482 (0.674-3.257) | 0.328 |
| IDO1-decline vs. IDO1-rise | 0.529 (0.279-1.006) | 0.052 | 0.815 (0.410-1.621) | 0.560 |
| H-ΔCD8 vs. L-ΔCD8 | 1.898 (1.000-3.603) | 0.050 | 1.510 (0.763-2.986) | 0.237 |
| pN staging (N+ vs. N0) | 3.409 (1.754-6.625) | <0.001 | 2.787 (1.356-5.729) | 0.005 |