Table 2. Patient characteristics.
| Characteristic | Total population (n=80) | Non-LV remodeling (n=58, 72.5%) | LV remodeling (n=22, 27.5%) | χ2 | P value |
|---|---|---|---|---|---|
| Age, years | 55.6±10.2 | 55.5±10.3 | 56.0±10.2 | –0.200 | 0.842 |
| Female, n (%) | 14 (17.5) | 11 (18.9) | 3 (13.6) | 0.314 | 0.575 |
| Body mass index | 26.0±3.8 | 26.0±3.9 | 26.0±3.5 | –0.009 | 0.993 |
| Hypertension, n (%) | 34 (42.5) | 24 (41.4) | 10 (45.5) | 0.108 | 0.742 |
| Diabetes mellitus | 24 (30.0) | 15 (25.9) | 9 (40.9) | 1.720 | 0.190 |
| Family history for AMI, n (%) | 20 (25.0) | 15 (25.9) | 5 (22.7) | 0.084 | 0.772 |
| COPD, n (%) | 5 (6.3) | 3 (5.2) | 2 (9.1) | 0.418 | 0.518 |
| Current smoker, n (%) | 59 (73.8) | 40 (72.4) | 19 (77.3) | 0.195 | 0.659 |
| Peak CK-MB (U/L) | 140.9 (79.9–260.9) | 118 (64.3–243.1) | 174.6 (120.4–343.7) | –2.069 | 0.039 |
| Peak troponin T (ng/mL) | 3.2 (1.3–6.0) | 2.6 (0.7–4.2) | 4.6 (3.5–9.0) | –3.286 | 0.001 |
| Peak logNT-proBNP (pg/mL) | 2.5 (2.0–3.1) | 2.3 (1.9–2.8) | 3.0 (2.6–3.3) | –3.464 | 0.001 |
| miR-1 expression | 2.7 (1.2–7.1) | 2.0 (1.1–5.6) | 6.0 (2.6–7.4) | –2.424 | 0.015 |
| miR-1 groups, n (%) | 8.788 | 0.004 | |||
| <2.03 | 32 (40.0) | 29 (50.0) | 3 (13.6) | ||
| ≥2.03 | 48 (60.0) | 29 (50.0) | 19 (86.4) | ||
| Culprit lesion, n (%) | 0.635 | 0.999 | |||
| RCA | 28 (35.0) | 20 (34.5) | 8 (36.4) | ||
| LAD | 38 (47.5) | 27 (46.6) | 11 (50.0) | ||
| LCX | 13 (16.3) | 10 (17.2) | 3 (13.6) | ||
| RI | 1 (1.3) | 1 (1.7) | 0 (0.0) | ||
| Time from symptom onset to PPCI (min) | 180 (83–271) | 180 (73–270) | 143 (90–271) | –0.151 | 0.880 |
| Pre-interventional TIMI flow | 1.090 | 0.872 | |||
| 0 | 62 (77.5) | 46 (79.3) | 16 (72.7) | ||
| 1 | 4 (5) | 4 (6.9) | 2(9.1) | ||
| 2 | 8 (10) | 5 (8.6) | 3 (13.6) | ||
| 3 | 6 (7.5) | 3 (5.2) | 1 (4.5) | ||
| Medication prior to admission | |||||
| Aspirin | 15 (18.7) | 8 (13.8) | 7 (31.8) | 3.402 | 0.065 |
| ACEI/ARB | 27 (33.8) | 20 (32.8) | 7 (36.4) | 0.051 | 0.821 |
| Beta-blockers | 20 (25) | 15 (25.9) | 5 (22.7) | 0.084 | 0.772 |
| Statins | 23 (28.8) | 15 (25.9) | 8 (36.4) | 0.859 | 0.354 |
| Metformin | 18 (22.5) | 12 (20.7) | 6 (27.3) | 0.396 | 0.529 |
AMI, acute myocardial infarction; COPD, chronic obstructive pulmonary disease; CK-MB, creatine kinase-MB; NT-proBNP, N-terminal pro-brain natriuretic peptide; RCA, right coronary artery; LAD, left anterior descending artery; LCX, left circumflex artery; RI, ramus intermedius; PPCI, primary percutaneous coronary intervention; TIMI, Thrombolysis in Myocardial Infarction; ACEI/ARB, angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers.