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. 2020 Jul 7;11:337. doi: 10.3389/fendo.2020.00337

Table 3.

Isoenergetic short/medium-term studies on the effects of dietary carbohydrate quality and quantity, and of dietary fat amount on postprandial lipemia.

Reference Study population Study design Intervention Duration Challenge Outcomes postprandial TAG increment
CHO %TEI Sugars %TEI Fiber g/day Fats %TEI
(45) 10 Healthy W Randomized cross-over Low-CHO 10 3 12 60 4 weeks Oral fat tolerance test High-CHO equal to low-CHO
High-CHO 55 25 20 25
(12) 10 T2D M Randomized cross-over High-MUFA 40 17 26 45 6 weeks Oral fat tolerance test High-CHO equal to low-CHO
High-CHO 55 23 36 30
(46) 88 M/W dyslipidaemia and/or IR Cross-over Low-MUFA 49 18 22 37 7 weeks High-fat test meal Low-MUFA equal to high-MUFA equal to high-CHO
High-MUFA 49 18 22 36
High-CHO 54 19 34 30
(47) 12 T2D Randomized cross-over High-MUFA 45 n.r. 25 40 6 weeks High-fat test meal High-MUFA equal to high-CHO
High-CHO 55 n.r. 25 30
(48) 8 post-obese 10 healthy W Randomized cross-over Low-CHO 41 2 32 46 2 weeks Breakfast, lunch and dinner with the same composition of the followed diet Low-CHO greater than high-sugar and high-starch
High-starch 59 2 22 28
High- sugar 59 23 20 18
(49) 18 T2D Randomized cross-over High-MUFA 45 10 16 37 4 weeks Test-meal with the same composition of the followed diet High-MUFA greater than high-fiber
High-fiber 52 10 54 30
(50) 45 T2D Randomized parallel groups High-MUFA 40 10 16 42 8 weeks Test-meal with the same composition of the followed diet High-MUFA greater than high-fiber
High-fiber 53 10 52 28
(51) 65 M/W MetS Randomized parallel groups Whole-grain 51 n.r. 20 32 12 weeks Test-meal with the same composition of the followed diet Refined-grain greater than whole-grain
Refined-grain 50 n.r. 40 33

CHO, carbohydrates; TEI, total energy intake; TAG, triglyceride; W, women; T2D, type 2 diabetes; M, men; IR, Insulin Resistance; n.r., not reported; MetS, Metabolic Syndrome.