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Concentration of copper and zinc ions within phagolysosomes of peritoneal macrophages during infection by three Mycobacterium spp.
| Element | Time | M. smegmatis | M. avium | M. tuberculosis |
|---|---|---|---|---|
| Cu | 1 h | 9.9 ± 5.5 μM | 28.3 ± 11.4 μM | 426 ± 393 μM |
| 24 h | 24.8 ± 0.65 μM | 17.3 ± 10.3 μM | 24.7 ± 9.5 μM | |
| Zn | 1 h | 70.5 ± 37.3 μM | 134.6 ± 38.8 μM | 37.8 ± 25.2 μM |
| 24 h | 260 ± 117 μM | 120.8 ± 31.1 μM | 459 ± 271 μM |
Concentrations were determined using hard x-ray microprobe with sub-optical resolution (Wagner et al., 2005).
