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. 2020 Jul 7;14:708. doi: 10.3389/fnins.2020.00708

TABLE 2.

Comparison between mMCAi and non-mMCAi patients in the training and validation sets.

Variable Training (n = 87) Validation (n = 39)


mMCAi (n = 36) Non-mMCAi (n = 51) P-value mMCAi (n = 16) Non-mMCAi (n = 23) P-value
Male sex, n (%) 22(61.11%) 32(62.75%) 0.878 10(62.50%) 15(65.22%) 0.864
Age, y; mean ± SD 75.14 ± 12.60 70.55 ± 14.67 0.403 72.06 ± 10.42 70.78 ± 11.26 0.799
Baseline NIHSS, median (IQR) 23(19.25–27) 17(14–21) 0.001 18.50(16.25–21.75) 16(7–18) 0.028
Hypertension, n (%) 26(72.22%) 36(70.59%) 0.869 7(43.75%) 14(60.87%) 0.342
Diabetes mellitus, n (%) 9(25.00%) 10(19.61%) 0.604 1(6.25%) 3(13.04%) 0.631
Hyperlipidemia, n (%) 11(30.56%) 9(17.65%) 0.199 3(18.75%) 4(17.39%) 0.915
Atrial fibrillation, n (%) 21(58.33%) 20(39.22%) 0.087 10(62.50%) 11(47.83%) 0.516
Smoking, n (%) 9(25.00%) 22(43.14%) 0.112 7(43.75%) 4(17.39%) 0.146
Alcohol abuse, n (%) 6(16.67%) 13(25.49%) 0.432 5(31.25%) 2(8.70%) 0.101
ASPECTS on NCCT, median (IQR) 5(1.25–8) 8(5–10) <0.001 3.50(1.25–5.75) 8(7–10) < 0.001
HVS of MCA, n (%) 23(63.89%) 26(50.98%) 0.276 12(75.00%) 7(30.43%) 0.010
Hemorrhage transformation, n (%) 13(36.11%) 20(39.22%) 0.825 8(50.00%) 10(43.48%) 0.752
Collateral score, median (IQR) 1(1–1) 1(1–1) 0.051 1(1–1) 1(1–1) 0.767
Right side of the MCA M1 occlusion, n (%) 18(50.00%) 24(47.06%) 0.830 12(75.00%) 11(47.83%) 0.111
ICA occlusion, n (%) 20(55.56%) 16(31.37%) 0.029 10(62.50%) 5(21.74%) 0.018
Rad score, mean ± SD 1.82 ± 4.12 −1.65 ± 1.64 0.020 1.59 ± 3.67 −1.02 ± 1.03 0.001

SD, standard deviation; NIHSS, National Institutes of Health Stroke Scale; IQR, interquartile range; ASPECTS, Alberta Stroke Program Early CT Score; NCCT, non-contrast computed tomography; HVS, hyperdense vessel sign; MCA, middle cerebral artery; ICA, internal carotid artery.