TABLE 2.
Comparison between mMCAi and non-mMCAi patients in the training and validation sets.
| Variable | Training (n = 87) | Validation (n = 39) | ||||
| mMCAi (n = 36) | Non-mMCAi (n = 51) | P-value | mMCAi (n = 16) | Non-mMCAi (n = 23) | P-value | |
| Male sex, n (%) | 22(61.11%) | 32(62.75%) | 0.878 | 10(62.50%) | 15(65.22%) | 0.864 |
| Age, y; mean ± SD | 75.14 ± 12.60 | 70.55 ± 14.67 | 0.403 | 72.06 ± 10.42 | 70.78 ± 11.26 | 0.799 |
| Baseline NIHSS, median (IQR) | 23(19.25–27) | 17(14–21) | 0.001 | 18.50(16.25–21.75) | 16(7–18) | 0.028 |
| Hypertension, n (%) | 26(72.22%) | 36(70.59%) | 0.869 | 7(43.75%) | 14(60.87%) | 0.342 |
| Diabetes mellitus, n (%) | 9(25.00%) | 10(19.61%) | 0.604 | 1(6.25%) | 3(13.04%) | 0.631 |
| Hyperlipidemia, n (%) | 11(30.56%) | 9(17.65%) | 0.199 | 3(18.75%) | 4(17.39%) | 0.915 |
| Atrial fibrillation, n (%) | 21(58.33%) | 20(39.22%) | 0.087 | 10(62.50%) | 11(47.83%) | 0.516 |
| Smoking, n (%) | 9(25.00%) | 22(43.14%) | 0.112 | 7(43.75%) | 4(17.39%) | 0.146 |
| Alcohol abuse, n (%) | 6(16.67%) | 13(25.49%) | 0.432 | 5(31.25%) | 2(8.70%) | 0.101 |
| ASPECTS on NCCT, median (IQR) | 5(1.25–8) | 8(5–10) | <0.001 | 3.50(1.25–5.75) | 8(7–10) | < 0.001 |
| HVS of MCA, n (%) | 23(63.89%) | 26(50.98%) | 0.276 | 12(75.00%) | 7(30.43%) | 0.010 |
| Hemorrhage transformation, n (%) | 13(36.11%) | 20(39.22%) | 0.825 | 8(50.00%) | 10(43.48%) | 0.752 |
| Collateral score, median (IQR) | 1(1–1) | 1(1–1) | 0.051 | 1(1–1) | 1(1–1) | 0.767 |
| Right side of the MCA M1 occlusion, n (%) | 18(50.00%) | 24(47.06%) | 0.830 | 12(75.00%) | 11(47.83%) | 0.111 |
| ICA occlusion, n (%) | 20(55.56%) | 16(31.37%) | 0.029 | 10(62.50%) | 5(21.74%) | 0.018 |
| Rad score, mean ± SD | 1.82 ± 4.12 | −1.65 ± 1.64 | 0.020 | 1.59 ± 3.67 | −1.02 ± 1.03 | 0.001 |
SD, standard deviation; NIHSS, National Institutes of Health Stroke Scale; IQR, interquartile range; ASPECTS, Alberta Stroke Program Early CT Score; NCCT, non-contrast computed tomography; HVS, hyperdense vessel sign; MCA, middle cerebral artery; ICA, internal carotid artery.