Table 2.
Diagnostic accuracy of the LUS score on the 7th and 28th DOL for the primary (moderate–severe BPD, sBPD) and secondary outcomes (BDP of any grade and CPAP dependency on the 28th DOL).
| AUC (95% CI) | Optimal cutoff | Se | Sp | LR+ | LR− | |
|---|---|---|---|---|---|---|
| LUS score (7th DOL) | ||||||
| sBPD | 0.94 (0.87–1) | ≥8 | 93 | 91 | 10.3 | 0.07 |
| Any grade BPD | 0.93 (0.86–1) | ≥5 | 90 | 81 | 3.6 | 0.12 |
| CPAP dependency | 0.89 (0.74–1) | ≥9 | 89 | 91 | 9.9 | 0.12 |
| LUS score (28th DOL) | ||||||
| sBPD | 0.92 (0.83–1) | ≥6 | 85 | 82 | 4.7 | 0.18 |
| Any grade BPD | 0.96 (0.9–1) | ≥4 | 95 | 86 | 6.8 | 0.06 |
| CPAP dependency | 0.97 (0.91–1) | ≥8 | 100 | 91 | 11.1 | 0 |
Se sensitivity, Sp specificity, LR+ positive likelihood ratio, LR− negative likelihood ratio.