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. 2020 Jul 7;10:980. doi: 10.3389/fonc.2020.00980

Table 3.

Relationship between tertiary lymphoid structure (TLS) and clinicopathological parameters.

Clinicopathological parameters TLS-SUM χ2 P value TLS-CT-D χ2 P value TLS-IM-N χ2 P value
High Low High Low High Low
Age (year)
    >50 387 403 2.389 0.122 410 380 2.091 0.148 405 385 0.057 0.811
     ≤ 50 70 54 73 51 65 59
Tumor size (cm)
    >5 220 250 3.942 0.047 225 245 9.599 0.002 250 220 1.212 0.271
     ≤ 5 237 207 258 186 220 224
Lymph node metastasis
    Yes 271 292 2.040 0.153 290 273 1.048 0.306 299 264 1.668 0.196
    No 186 165 193 158 171 180
Vessel invasion
    Yes 157 158 0.005 0.945 155 160 2.553 0.110 169 146 0.956 0.328
    No 300 299 328 271 301 298
Histological grade
     Well 22 20 6.512 0.039 26 16 7.396 0.025 17 25 2.795 0.247
    Moderately 146 183 155 174 165 164
    Poor 289 254 302 241 288 255
pTN stage
    I 127 109 6.226 0.044 139 97 14.531 0.001 104 132 9.808 0.007
    II 120 154 119 155 137 137
    III 210 194 225 179 229 175
WHO subtypes
    Tubular 296 277 24.119 <0.001 309 264 15.867 0.003 304 269 7.781 0.100
    Mucinous 37 48 47 38 40 45
    Papillary 9 39 13 35 16 32
    Poorly cohesive 84 62 85 61 78 68
    Undifferentiated 31 31 29 33 32 30

Values in bold signify p < 0.05.