Table 5.
Strain | Sex | Age |
vCa |
vPHOS |
vK |
vNa |
iNa |
iK |
iCl |
iCa |
iAnGap |
---|---|---|---|---|---|---|---|---|---|---|---|
(mg/dL) | (mmol/L) | ||||||||||
Cobb | 11.52 | 7.27 | 7.36 | 148.1 | 143.6 | 4.93 | 108.3 | 1.36 | 16.2 | ||
Ross | 11.48 | 7.32 | 8.12 | 149.2 | 144.1 | 4.96 | 108.6 | 1.35 | 16.4 | ||
P < | 0.171 | 0.721 | <0.001 | 0.199 | 0.011 | 0.484 | 0.062 | 0.386 | 0.557 | ||
Male | 11.48 | 7.35 | 7.78 | 148.3 | 143.6 | 5.01 | 107.6 | 1.35 | 16.4 | ||
Female | 11.53 | 7.23 | 7.70 | 149.0 | 144.1 | 4.88 | 109.1 | 1.36 | 16.3 | ||
P < | 0.802 | 0.380 | 0.409 | 0.807 | 0.015 | 0.140 | 0.009 | 0.071 | 0.631 | ||
14 d | 11.43bc | 6.11c | 6.69cd | 146.1b | 140.9c | 5.55a | 110.6a | 1.26c | 12.9b | ||
21 d | 11.97a | 7.45ab | 7.14bc | 149.6a | 144.0b | 5.11b | 108.3ab | 1.39a | 17.2a | ||
28 d | 11.26bc | 7.91a | 8.17ab | 148.1b | 143.5b | 4.63cd | 107.0b | 1.33b | 16.9a | ||
35 d | 11.72ab | 7.26b | 9.07a | 149.5a | 145.5a | 4.52d | 106.7b | 1.39a | 16.8a | ||
42 d | 11.13c | 7.74ab | 7.64d | 149.8a | 145.3a | 4.94bc | 108.9ab | 1.39a | 17.8a | ||
P < | <0.001 | <0.001 | <0.001 | 0.022 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | ||
Linear P < | 0.032 | <0.001 | <0.001 | 0.012 | <0.001 | <0.001 | 0.021 | <0.001 | <0.001 | ||
Quadratic P < | 0.027 | <0.001 | <0.001 | 0.421 | <0.001 | <0.001 | <0.001 | 0.010 | <0.001 | ||
Model Pooled SEM1 | 0.25 |
0.32 |
0.48 |
1.9 |
0.5 |
0.19 |
1.3 |
0.02 |
0.5 |
||
Interaction Terms | (Probability > F) | ||||||||||
Strain∗Age | 0.691 | 0.923 | 0.005 | 0.138 | 0.319 | 0.673 | 0.248 | 0.275 | 0.461 | ||
Sex∗Age | 0.026 | 0.778 | 0.487 | 0.487 | 0.967 | 0.017 | 0.218 | 0.244 | 0.027 | ||
Strain∗Sex | 0.001 | 0.080 | 0.773 | 0.886 | 0.398 | 0.804 | 0.302 | 0.064 | 0.711 | ||
Strain∗Age∗Sex | 0.002 | 0.023 | 0.173 | 0.063 | 0.131 | 0.519 | 0.566 | 0.655 | 0.143 |
ab Means within a column of 3 or more independent variables lacking a common superscript differ significantly (P < 0.05).
SEM = Standard error of mean, main effect means of strain and sex calculated using n = 200, main effect means of age calculated using n = 80.