Table 1.
DA, DOPAC and HVA concentration levels (ng/mg ww) and DA turnover in the striatum of mice.
| Analytes or ratio | Control females1 | Control males2 | MPTP females1 | MPTP males3 |
|---|---|---|---|---|
| DA | 10.255 ± 2.451 | 10.692 ± 1.983 | 3.995 ± 2.364 | 1.651 ± 0.830 |
| DOPAC | 0.989 ± 0.170 | 1.097 ± 0.273 | 0.496 ± 0.248 | 0.195 ± 0.135 |
| HVA | 1.781 ± 0.453 | 1.938 ± 0.696 | 1.039 ± 0.458 | 0.604 ± 0.388 |
| (DOPAC + HVA)/DA | 0.276 ± 0.048 | 0.295 ± 0.062 | 0.440 ± 0.167 | 0.527 ± 0.227 |
Data are presented as mean (±S.D.); 1n = 14; 2n = 15; 3n = 13; DA dopamine; DOPAC 3,4-dihydroxyphenylacetic acid; HVA homovanillic acid; MPTP 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; ww wet weight.