Table 1.

Advantages of the suggested recombinant protein.

Advantage	Explanation
Gain of specificity at 100%	The use of ACE-2 ectodomain guaranties the same binding affinity
It avoids side effects	No chemical compound unlike drugs
It is based on innate immune system reactions	Opsonization and phagocytosis
It doesn’t create a cross reactivity of the immune system against the recombinant protein	Both of proteins are human; part of the body
It doesn’t require many technologies neither a lot of stages	Monoclonal antibodies production holds many steps and take more time
It could be applied for eventual new receptors engaged as an entry way of SARS-CoV-2	The ectodomain will be changed according to the new receptor