Table 3.
Sensitivity, specificity, PPV, and NPV of the most commonly used criteria for the electrocardiographic detection of LVH in the diagnosis of eccentric and concentric LVH
| LVH Criterion | Eccentric LVH | Concentric LVH | LVH | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | |
| SL voltage | – | – | – | – | 1 | 98.7 | 5 | 93.5 | 0.7 | 98.7 | 5 | 90.7 |
| SL product | 4.4 | 98.5 | 8 | 97.2 | 3.9 | 98.6 | 16 | 93.7 | 4.1 | 98.7 | 24 | 91 |
| SL index | 6.7 | 95.8 | 4.4 | 97.2 | 8.7 | 96 | 13.2 | 93.8 | 8.2 | 96.1 | 17.6 | 91.1 |
| Cornell voltage | 11.1 | 94.8 | 5.8 | 97.3 | 16.5 | 95.4 | 19.8 | 94.3 | 14.9 | 95.6 | 25.6 | 91.6 |
| Cornell product | 17.8 | 89.6 | 4.7 | 97.4 | 28.2 | 90.6 | 17.2 | 94.8 | 25 | 90.9 | 21.9 | 92.2 |
| Lewis voltage | 15.6 | 90.6 | 4.6 | 97.4 | 16.5 | 90.9 | 11.2 | 94 | 16.2 | 91.1 | 15.8 | 91.4 |
| Framingham | 2.2 | 99.7 | 16.7 | 97.2 | 1 | 99.7 | 16.7 | 93.6 | 1.4 | 99.8 | 33.3 | 91.6 |
Abbreviations: LVH, left ventricular hypertrophy; PPV, positive predictive value; NPV, negative predictive value; SL, Sokolow–Lyon.