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. 2020 May 29;6(7):1951–1964. doi: 10.1021/acsinfecdis.0c00252

Table 2. SAR and in Vitro ADMET Data for RHS Modifications.

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a

14 day readout against the H37Rv Mtb-GFP strain in GASTE-Fe media.

b

clogD calculated using StarDrop.

c

Kinetic solubility assay at pH 7.4 using the HPLC method.

d

H/R/M: human/rat/mouse. ND: Not determined.