Table 5. Description of Mutations Obtained from Spontaneous -Resistant Mutant Generation.
no. | MIC90 of 2 (μM) | gene | mutation | descriptor |
---|---|---|---|---|
1 | >160 | glpK | SNP | T96M |
2 | >160 | glpK | frameshift mutation | C insertion at a.a. 189 |
3 | >160 | glpK | frameshift mutation | C insertion at a.a. 189 |
4 | >160 | glpD2 | SNP | F122V |
5 | >160 | glpD2 | SNP | F122L |
6 | >160 | glpD2 | SNP | F122L |