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Development of αvβ3 targeted MI3 prodrug perfluorocarbon nanoparticles (PFC). (A) PFC nanoparticles deliver MI3 prodrug through a contact-facilitated drug delivery mechanism. (B) Analysis of the average PFC nanoparticle diameter, polydispersity and zeta potential (C) MYC/MAX dimerization inhibitor MI3 prodrug (D) MYC inhibitor MI3 (E) αvβ3-integrin targeting ligand.
