Table 5.

Binarized baseline PSMA PET parameters and overall survival

	Measurement selected per patient	Ideal cut-off	P	Below cut-off			Above cut-off
				n	Median Survival	95%CI	n	Median Survival	95%CI
SUVmax	Average (=PSMAaverage)	14.3	<0.001	20	5.3	2.3-8.8	65	15.1	7.8-23.4
	Highest (=PSMAmax)	n.a.	n.s.
	Lowest (=PSMAmin)	10.2	0.003	69	7.9	4.6-11.2	16	21.3	n.a.
	Std (=PSMAstd)	3.0	<0.001	9	3.2	0.0-6.9	76	13.2	9.0-17.4
SUVmax / SUVmean liver	Average	6.2	0.003	42	7.2	5.8-8.6	43	21.3	13.2-29.3
	Highest	n.a.	n.s.
	Lowest	n.a.	n.s.
	Std	n.a.	n.s.
SUVmean	Average	9.3	<0.001	17	6.4	1.7-11.1	68	15.1	10.1-20.1
	Highest	n.a.	n.s.
	Lowest	7.1	0.004	65	8.6	4.3-12.9	20	25.5	15.1-36.0
	Std	1.9	<0.001	9	3.2	0.0-6.9	76	13.2	9.1-17.4
SUVpeak	Average	9.7	<0.001	19	6.4	3.7-9.1	66	13.2	8.4-18.1
	Highest	n.a.	n.s.
	Lowest	6.6	0.004	65	8.6	4.3-12.9	20	25.5	15.1-36.0
	Std	n.a.	n.s.

Abbreviations: CI = confidence interval; Std = standard deviation; n.a. = not available; n.s. = not statistically significant. Bonferroni adjustment: p < 0.0125 is regarded statistically significant. Ideal cut-off was found by log rank cut-off finder.