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Receiver operating characteristic analysis curves denoting CSF CCL2, CSF NfL, and hippocampal volume for rapid cognitive decline (≥ 3 CDR SB change over two years, highest quartile among subjects) from ADNI cohort. Base models of the three biomarkers alone and adjusted models accounting for age, sex, years of education, APOE ɛ4 genotype, and CSF Aβ1–42/p‐tau.
