Figure 3.
RT‐qPCR analysis of genes involved in Regulation of Actin Cytoskeleton in SMA type 3 patients (n = 31) and healthy controls (n = 34). (A) PAK6, PXN, APC, CRK, F2R, KRAS, BRAF, FGF9, IQGAP2, (B) ACTB, (C) ACTA1, ACTA2, ACTC1, ACTG1, and (D) RHOA and ROCK1 mRNA expression. Unpaired Student’s t tests were used to compare groups. *P ≤ 0.05; **P ≤ 0.01; ****P ≤ 0.0001