Table 3.
Incidence rate ratio and hazard rate of autoimmune diseases in patient with and without thymectomy.
|
Event (n/%) (any type ADs) |
Person Year | IR 1 | IRR | Adjusted HR 2 | |||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P‐Value | |||||
| Thymectomy | |||||||
| Yes | 39 (17.1) | 8803 | 443.04 | 2.68 | 2.65 | 1.880–3.728 | <0.0001 |
| No | 189 (82.9) | 114,306 | 165.35 | Ref. | Ref. | ||
|
Event (n/%) (organ specifc ADs) |
Person Year | IR 1 | IRR | Adjusted. HR 2 | |||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P‐Value | |||||
| Thymectomy | |||||||
| Yes | 17 (7.4) | 8919 | 190.60 | 3.04 | 3.00 | 1.761–5.099 | <0.0001 |
| No | 72 (31.6) | 114,815 | 62.71 | Ref. | Ref. | ||
|
Event (n/%) (systemic ADs) |
Person Year | IR 1 | IRR | Adjusted HR 2 | |||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P‐Value | |||||
| Thymectomy | |||||||
| Yes | 24 (10.5) | 8866 | 270.69 | 2.59 | 2.56 | 1.648–3.982 | <0.0001 |
| No | 120 (52.6) | 114,578 | 104.73 | Ref. | Ref. | ||
IR, incidence rate; IRR, incidence rate ratio; HR, hazard ratio.
1
Per 100,000 person year.
2
Adjusted HR was adjusted by gender, age group.