Fig. 1.

ICH was induced in male CD1 mice, as detailed in the “Methods” section, and the susceptibility-weighted (a), as well as T2-weighted (b), magnetic resonance (MR) image depicts ICH-mediated induction of hematoma as well as the hemorrhagic lesion, respectively, in the mouse brain striatum on day 3 post-surgery (scale bar = 1 mm). The induction of ICH resulted in significant neurobehavioral deficits, which was estimated using a 24-point scale as detailed in methods, on day 3 post-surgery in comparison to sham that served as the experimental control (c). n = 8–9/animals per group. ***p < 0.001 vs. sham