Table 2.
Non-PH (n=7) | Mild-moderate PH (n=13) | Severe PH (n=18) | All patients (n=38) | |
Age (years) | 67±5 | 67±8 | 61±8 | 65±8 |
Gender (M/F) | 6/1 | 8/5 | 12/6 | 26/12 |
FEV1/FVC (%) | 85±6 | 77±14 | 76±16 | 78±14 |
FEV1* | 54±15 | 55±17 | 54±21 | 54±18 |
FVC* | 47±11 | 55±19 | 56±22 | 53±19 |
TLC* | 48±12 | 50±16 | 58±16 | 53±15 |
RV* | 41±16 | 47±29 | 59±20 | 51±23 |
DLCO* | 27±14 | 24±11 | 21±9 | 22±10 |
mPAP (mm Hg) | 17±3† | 26±2† | 49±12† | 35±16 |
PVR (WU) | 2.76±1.4 | 3.37±1.14 | 9.13±6.09‡ | 5.9±5.1 |
*Per cent of predicted.
†Statistically significant between all groups comparisons.
‡Statistically significant between none and mild/moderate to severe PH groups.
DLCO, lung diffusion of carbon monoxide; FEV1, forced expiratory volume in the first second; FVC, forced vital capacity; mPAP, mean pulmonary artery pressure; PH, pulmonary hypertension; PVR, pulmonary vascular resistance; RV, residual volume; TLC, total lung capacity; WU, Wood units.