Table 3.
Comparison of patients’ characteristics between patients with and without plexiform lesions
| Patients with plexiform lesions (n=8) | Patients without plexiform lesions (n=30) | |
| Age (years) | 65±7 | 63±11 |
| Gender (M/F) | 6/2 | 20/10 |
| Lung disease (IPF/non-IPF) | 2/6 | 13/17 |
| FEV1/FVC (%) | 78±15 | 81±13 |
| FEV1* | 55±18 | 53±22 |
| FVC* | 54±18 | 52±23 |
| TLC* | 53±17 | 56±12 |
| RV* | 50±24 | 59±21 |
| DLCO* | 21±9 | 28±14 |
| mPAP (mm Hg) | 33±12 | 43±25 |
| PVR (WU) | 5±3 | 9±10 |
| H&E vascular grade | 4 | 2±0.7† |
*Per cent of predicted.
†Statistically significant.
DLCO, lung diffusion of carbon monoxide; FEV1, forced expiratory volume in the first second; H&E, Heath and Edwards pulmonary vasculopathy grades; IPF, idiopathic pulmonary fibrosis; mPAP, mean pulmonary artery pressure; PVR, pulmonary vascular resistance; RV, residual volume; TLC, total lung capacity; WU, Wood units.