Table 1.
Clinical baseline parameters and 2D echocardiographic characteristics between HCM patients and normal subjects (mean ± SD)
| Variable | Values | P Value | |
|---|---|---|---|
| HCM(32) | Normal(34) | ||
| Clinical baseline parameters | |||
| Age (years) | 47 ± 14 | 46 ± 12 | 0.779 |
| Male | 19 (32) | 19 (34) | |
| Heart Rate (bpm) | 70 ± 11 | 72 ± 12 | 0.391 |
| NYHA Class | |||
| I | (30)32 | ||
| II | (2)32 | ||
| III | (0)32 | ||
| IV | (0)32 | ||
| Medical treatment | |||
| β-Blockers | (27)32 | ||
| Calcium channel blockers | (5)32 | ||
| Disopyramide | (0)32 | ||
| Diuretics | (0)32 | ||
| ICD | (0)32 | ||
| 2D echocardiographic characteristics | |||
| LAd (mm) | 42.06 ± 4.91 | 35.09 ± 3.38 | < 0.001 |
| IVDd (mm) | 19.41 ± 4.09 | 9.21 ± 1.04 | < 0.001 |
| LVPWd (mm) | 10.19 ± 1.15 | 9.21 ± 1.04 | 0.001 |
| LVEF(%) | 66.59 ± 6.39 | 65.20 ± 5.30 | 0.339 |
| RVWd (mm) | 2.50 ± 0.51 | 2.47 ± 0.51 | 0.815 |
| RVd middle (mm) | 29.28 ± 4.26 | 27.59 ± 3.02 | 0.066 |
| RVd longitudinal (mm) | 52.31 ± 4.40 | 52.02 ± 5.16 | 0.812 |
| RVd basal (mm) | 25.09 ± 3.44 | 24.62 ± 3.19 | 0.562 |
| sPAP (mmHg) | 20.50 ± 4.69 | 18.56 ± 4.44 | 0.090 |
| RAd middle (mm) | 37.09 ± 3.89 | 37.82 ± 3.83 | 0.445 |
| RAd longitudinal (mm) | 48.93 ± 4.43 | 46.74 ± 3.42 | 0.027 |
| TAPSE (mm) | 21.25 ± 2.06 | 21.94 ± 1.97 | 0.169 |
| E | 0.48 ± 0.12 | 0.57 ± 0.09 | 0.001 |
| A | 0.42 ± 0.09 | 0.40 ± 0.07 | 0.268 |
| E/A | 1.19 ± 0.34 | 1.47 ± 0.28 | 0.001 |
| S′(cm/s) | 10.41 ± 1.89 | 9.92 ± 1.42 | 0.234 |
| E′ (cm/s) | −7.53 ± 2.04 | −8.74 ± 1.79 | 0.013 |
| A′ (cm/s) | −11.13 ± 2.20 | −10.53 ± 2.37 | 0.289 |
| E′/A′ | 0.71 ± 0.24 | 0.89 ± 0.34 | 0.016 |
| TR grade | |||
| Absence/Slight | (30)32 | (32)34 | |
| Mild | (2)32 | (2)34 | |
| Moderate | (0)32 | (0)34 | |
| Severe | (0)32 | (0)34 | |
Abbreviations: LAd left atrial diameter, IVDd inter-ventricle septal wall diameter in the diastole period, LVPWd left ventricular posterior wall diameter in the diastole period, LVEF left ventricular ejection fraction, RV right ventricular, RVd middle RV diameter at the middle level, RVWd RV free wall diameter, RVd longitudinal RV diameter at the longitudinal, RVd basal RV diameter at the base level, sPAP systolic pulmonary arterial pressure, RA right atrial, RAd middle RA diameter at the middle level, RAd longitudinal RA diameter at the longitudinal, TAPSE tricuspid annular plane systolic excursion, E Peak early velocities of tricuspid valve were measured by pulsed-wave Doppler, A Peak late velocities of tricuspid valve were measured by pulsed-wave Doppler, S′ peak systolic annular velocities obtained at RV lateral wall by using TDI, E′ peak early diastolic annular velocities obtained at RV lateral wall by using TDI, A′ peak late diastolic annular velocities at RV lateral wall by using TDI, TR tricuspid valve regurgitation