Table 3.
ROC analysis of CBF for differentiation between the PD and PPS groups
| Brain region | AUC | Cutoff point | Sensitivity (%) | Specificity (%) | 95% CI | p-value | |
|---|---|---|---|---|---|---|---|
| Upper bound | Lower bound | ||||||
| SMA.L | 0.831 | 33.723 | 0.800 | 0.750 | 0.696 | 0.967 | 0.001 |
| THA.R | 0.759 | 50.195 | 0.750 | 0.812 | 0.597 | 0.922 | 0.008 |
| CN. L | 0.725 | 24.544 | 0.900 | 0.625 | 0.547 | 0.903 | 0.022 |
| IFG_Tri.L | 0.719 | 39.483 | 0.650 | 0.875 | 0.545 | 0.892 | 0.026 |
| MFG.L | 0.694 | 44.581 | 0.550 | 0.937 | 0.521 | 0.866 | 0.048 |
Abbreviations: ROC, receiver operating characteristic; PD, Parkinson’s disease; PPS, Parkinsonism-Plus syndrome; AUC, area under the curve; CI, confidence interval; SMA, supplementary motor area; THA, thalamus; CN, caudate nucleus; IFG_Tri, triangle inferior frontal gyrus; MFG, middle frontal gyrus; L (R), left (right) hemisphere