Table 2.
Baseline clinical characteristics of the 785 patients included from the COREA cohort
| Age at asthma diagnosis < 40 years n = 245 |
Age at asthma diagnosis 40–59.9 years n = 316 |
Age at asthma diagnosis ≥ 60 years n = 224 |
p-value | |
|---|---|---|---|---|
| Age, years | 36.3 ± 11.6 | 54.4 ± 7.8 | 68.9 ± 5.3 | NA |
| Gender male | 103 (42.0%) | 141 (44.6%) | 118 (52.7%) | 0.055 |
| BMI kg·m−2 | 23.3 ± 3.6 | 24.6 ± 3.5 a | 24.6 ± 3.1 a | < 0.001 |
| Smoking status | ||||
| never smokers | 116 (48.5%) | 171 (55.2%) | 94 (42.9%) | < 0.001 |
| ex-smokers | 83 (34.3%) | 100 (31.3%) | 106 (48.4%) | |
| current smokers | 41 (17.2%) | 42 (13.6%) | 19 (8.7%) | |
| Pack-years | 4 ± 9 | 9 ± 16 a | 17 ± 24 a,b | < 0.001 |
| B-eosinophils ×109/L | 0.44 ± 0.40 | 0.33 ± 0.32 a | 0.28 ± 0.26 a | < 0.001 |
| IgE kU/L c | 422 ± 568 | 320 ± 576 | 378 ± 650 | 0.305 |
| Skin prick positive d | 115 (64.6%) | 85 (47.0%) | 18 (19.2%) | < 0.001 |
Data is shown as n (%) and mean ± SD. NA not analyzed, BMI body mass index, B blood, IgE immunoglobulin E
a: as compared to group: Age at asthma diagnosis < 40 years p < 0.05
b as compared to group: Age at asthma diagnosis 40–59.9 years p < 0.05.
c: data available on 461 patients. d: data available on 463 patients