Fig. 7. GAS5 increases the cisplatin sensitivity of CC cells in vivo.
a Tumour sizes were measured weekly, and volumes were calculated according to the following equation: width2 × length × 0.5. *P < 0.05, Student’s t-test. The data are shown as the means ± SDs (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001. b Mice were anaesthetized and photographed two weeks after tumorigenesis. c Mice were sacrificed and photographed at the eighth week after cell injection. d Tumour sizes in the lentivirus-GAS5 group were significantly lower than those in the lentivirus-NC group. One tumour in the lv-GAS5 group could not be found. e Xenograft tumour sections were subjected to haematoxylin and eosin (H&E) staining as well as immunohistochemical staining for PDCD4 (magnification, ×200). Scale bar, 50 μm.