Table 1.
Gene* | Fold change (Ig1 vs. Lympho) | Fold change (SSC4121 vs. Lympho) | Fold change (SSC8311 vs. Lympho) | Expression-Lympho_cont | Expression-Ig1 | Expression-SSC4121 | Expression-SSC8311 |
---|---|---|---|---|---|---|---|
ROBO1 | 745.647 | 91.2253 | 812.44 | 0.0128824 | 9.60575 | 1.1752 | 10.4662 |
NLRP2 | 112.939 | 124.576 | 905.512 | 0.0184944 | 2.08874 | 2.30397 | 16.7469 |
HOXB2 | 107.756 | 94.6583 | 91.1358 | 0.0847141 | 9.12846 | 8.0189 | 7.72049 |
IPCEF1 | 73.9769 | 49.2174 | 89.7259 | 0.219583 | 16.2441 | 10.8073 | 19.7023 |
PTK7 | 72.7466 | 22.561 | 122.293 | 0.0228934 | 1.66542 | 0.516499 | 2.79971 |
TLR4 | 72.0192 | 91.7155 | 63.094 | 0.0117378 | 0.845345 | 1.07654 | 0.740583 |
TBX15 | 63.2896 | 212.859 | 167.082 | 0.0388303 | 2.45756 | 8.26537 | 6.48786 |
ALOX12P2 | 52.9232 | 58.8549 | 52.5783 | 0.0490289 | 2.59477 | 2.88559 | 2.57786 |
TLR2 | 49.104 | 83.3778 | 275.744 | 0.00997296 | 0.489712 | 0.831523 | 2.74999 |
IGFBP2 | 44.1936 | 12.5067 | 5.84204 | 0.0949699 | 4.19706 | 1.18776 | 0.554818 |
LPAR6 | 34.7975 | 42.8991 | 35.26 | 0.441516 | 15.3636 | 18.9406 | 15.5678 |
AIF1 | 12.5361 | 8.50887 | 16.9555 | 0.156669 | 1.96403 | 1.33308 | 2.65641 |
FGFR1 | 6.50824 | 6.67026 | 6.91029 | 0.753597 | 4.90459 | 5.02669 | 5.20757 |
VSTM2L | −6.46587 | −7.61594 | −27.1737 | 2.19728 | 0.339827 | 0.28851 | 0.0808603 |
GRM3 | −17.1065 | −5.70896 | −11.9821 | 0.446002 | 0.026072 | 0.0781232 | 0.0372223 |
LOC151174 | −29.3255 | 2.94275 | −4.56462 | 0.554209 | 0.0188985 | 1.6309 | 0.121414 |
GPR98 | −31.1584 | −4.95165 | −21.8246 | 0.179003 | 0.00574493 | 0.0361501 | 0.00820188 |
HOMER3 | −36.3133 | −19.0099 | −135.655 | 4.0601 | 0.111807 | 0.213578 | 0.0299296 |
MYL9 | −64.4865 | −42.5937 | −19.0713 | 37.8958 | 0.587655 | 0.889704 | 1.98705 |
HMX3 | −75.6048 | −7.00876 | −2.882 | 10.4248 | 0.137885 | 1.4874 | 3.61722 |
CDH17 | No change | −95.1494 | No change | 2.49733 | 0 | 0.0262464 | 0 |
(*) Here, unlike the fold changes computed for GSEA analysis (“Methods”), we ranked genes by the highest fold change among the three mutated samples versus the control “Lympho” sample.