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. 2020 Jul 13;11:3488. doi: 10.1038/s41467-020-17155-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a auPRC comparison for the context window sizes 500 bp and 2000 bp for tri-nucleotide based sequence encoding. The mark color indicates the feature types: DNase hypersensitive sites, histone modifications and transcription factor binding assays. b auPRC comparison for tri- and mono-nucleotide based sequence encoding for a context window of 2000 bp. Color coding as above. c Differences in auPRC between tri- and mono-nucleotides for DNase accessibility, histone modifications and transcription factor binding, respectively. ΔauPRC > 0 indicates improved performance for the tri-nucleotide based encoding. Dnase, histone modification and TF features comprise n = 125, n = 104, and n = 690 samples, respectively. Boxes represent quartiles Q1 (25% quantile), Q2 (median), and Q3 (75% quantile); whiskers comprise data points that are within 1.5 x IQR (inter-quartile region) of the boxes.