Table 2.
Incidence of bombesin receptor subtype expression in various human cancers (Reubi et al., 2002b).
| Tumor type | n cases | Receptor incidence | ||
|---|---|---|---|---|
| NMBR | GRPR | BRS-3 | ||
| Prostate carcinomas | 12 | 0/12 | 12/12 | 0/12 |
| Breast carcinomas | 57 | 0/57 | 41/57 | 0/57 |
| NEa GEP tumors | ||||
| Gastrinomas | 5 | 0/5 | 5/5 | 0/5 |
| Intestinal carcinoids | 24 | 11/24 | 0/24 | 0/24 |
| Thymic carcinoid | 1 | 1/1 | 0/1 | 0/1 |
| NE lung tumors | ||||
| Bronchial carcinoids | 26 | 1/26 | 0/26 | 9/26 |
| Small cell lung cancers | 9 | 0/9 | 3/9 | 4/9 |
| LCNEC | 1 | 0/1 | 0/1 | 1/1 |
| Renal cell carcinomas | 16 | 0/16 | 6/16 | 4/16 |
| Ewing sarcomas | 10 | 0/10 | 0/10 | 2/10 |
a
NE, neuroendocrine; GEP, gastroenteropancreatic; LCNEC, large cell neuroendocrine carcinoma.