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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Radiat Res. 2020 Feb 19;193(4):305–317. doi: 10.1667/RADE-20-00013

Figure 3. KAP1 knockout amplified radiation induced activation of ISGs.

Figure 3.

(A). Immunoblot of dsRNA sensing pathway members in vector control or KAP1 knockout B16F10 cells 3 days post irradiation with sham or 8Gy X-rays.

(B) qRT-PCR quantification of interferon-stimulated genes in vector control or KAP1 knockout B16F10 cells 3 days post exposure to sham or 8Gy X-rays.

(C). Immunoblot of dsRNA sensing pathway members from KAP1/MAVS double knockout B16F10 cells 3 days after exposure to 8Gy X-rays.

Error bars represent SEM. *p,<0.05, **p<0.01, ***p<0.001, ns, not significant, as determined by unpaired Student’s T-test (B)