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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Radiat Res. 2020 Feb 19;193(4):305–317. doi: 10.1667/RADE-20-00013

Figure 4. KAP1 knockout inhibits B16F10 melanoma growth in syngeneic C57BL/6 and immunodeficient NSG mice.

Figure 4.

(A, B). Tumor growth (A) and Kaplan-Meier survival curve in immunocompetent C57BL/6 host mice(B) inoculated with 105 vector control or KAP1 knockout B16F10 cells and treated with 0Gy or 8Gy X-rays at day 8 post inoculation.

(C, D). Tumor growth (C) and survival curves (D) in immunodeficient NSG mice inoculated with 105 vector control or KAP1 knockout B16F10 cells.

Data in A&B represent three separate experiments. Error bars represent SEM. *p<0.05, **p<0.01, ***p<0.001, ns, not significant, as determined by one-way ANOVA (A and C) or Log-Rank test (B and D)