Table 1.

Summary of included studies

Study ID	Design	Population	Follow-up	Main findings
Dijos et al. [16]	Single center, prospective cohort study	198 patients with severe AS (19 with prior C-XRT)	6 months	Similar short-and mid-term mortalities between the comparison groups
Bouleti et al. [17]	Single center, prospective cohort study	52 patients with severe AS (26 with prior C-XRT)	5 years	Trends for higher short- and long-term mortalities in C-XRT group, but statistically not significant
Gajanana et al. [18]	Single center, prospective cohort study	1150 patients with severe AS (44 with prior C-XRT)	1 year	Similar short-term mortality in both groups, but higher 1-year mortality in C-XRT group
Agrawal et al. [10]	Observational study (STS/ACC TVT Registry)	610 patients with severe AS (75 with prior C-XRT)	17 months	Significantly higher in-hospital and long-term mortalities in the C-XRT group

STS/ACC TVT Registry- American College of Cardiology National Cardiovascular Data Registry; AS-aortic stenosis; C-XRT- prior chest radiation therapy