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[Preprint]. 2020 Sep 22:2020.07.06.190348. Originally published 2020 Jul 6. [Version 2] doi: 10.1101/2020.07.06.190348

PMC7359521.1; 2020 Jul 6
PMC7359521.2; 2020 Sep 22

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Figure 5. — SARS-CoV-2 genome titrates the abundance of functionally important miRs in human tissue (A) Violin plot shows the statistically significant (p-value < e-05) preferential binding profile of miR-motifs (sorted by frequency of binding >15 sites) across the SARS-CoV-2 viral genome (length normalized) identified using FIMO. (B) Hierarchically clustered heatmap showing the log10 expression (CPM, row normalized) of miRs across tissues. (C) Bar-plot illustrating the significant biological processes, obtained from gene ontology enrichment based functional grouping of miR target genes (obtained from miRNet). Significant clustering (adj. p < 1e-10) of genes enriched in GO-biological processes generated by ClueGO analysis (Cytoscape plugin).