Table 1.

Demographic and clinical features of MIS-C patients. Abbreviations, coronary artery (CA), major depressive disorder (MDD), post-traumatic stress disorder (PTSD), cardiomegaly (CM), mitral regurgitation (MR), left ventricle (LV), thrombocytopenia (TCP), reactive airway disease (RAD).

	P1	P2	P3	P4	P5	P6	P7	P8	Aggregate
Gender	Male	Female	Male	Female	Male	Male	Female	Female	50% Male
Comorbidities	none	none	Asthma	none	Asthma	none	MDD, PTSD	none	37.50%
WHO MIS-C Criteria
Fever	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	100%
Rash	No	Yes	No	Yes	Yes	No	No	No	37.50%
Conjunctivitis	Yes	Yes	No	No	No	No	No	Yes	37.50%
Mucocutaneous	Yes	Yes	No	Yes	No	No	No	No	37.50%
Extremity	No	No	No	No	No	No	No	No	0.00%
Gastrointestinal	Pain Emesis	Pain Emesis	Pain	Emesis Diarrhea	Diarrhea	Pain	Emesis Diarhhea	Pain Emesis	100%
Hypotension / shock	Yes	Yes	No	No	No	Yes	Yes	Yes	63%
Cardiac Abnormalities	↑ troponin ↑ BNP CA dilation MR	↑ troponin ↑ BNP	↑ troponin ↑ BNP Prolonged-PR CM	↑ troponin ↑ BNP	CA ectasia	↑ troponin ↑ BNP CA dilation	↑ troponin ↑ BNP CA aneurysm Reduced LV function Diffuse ST elevation	↑ troponin ↑ BNP CA aneurysm Reduced LV function Prolonged QT	100%
Coagulopathy	↑ D-dimer ↑ PT ↑ PTT	↑ D-dimer ↑ PT ↑ PTT	↑ D-dimer ↑ PT ↑ PTT	↑ D-dimer ↑ PT ↑ PTT	↑ D-dimer	↑ D-dimer ↑ PT ↑ PTT	↑ D-dimer ↑ PT ↑ PTT	↑ D-dimer ↑ PT ↑ PTT	87.50%
Inflammatory Markers	↑ ESR ↑ CRP ↑ PCT	↑ ESR ↑ CRP ↑ PCT	↑ ESR ↑ CRP	↑ ESR ↑ CRP ↑ PCT	↑ ESR ↑ CRP ↑ PCT	↑ ESR ↑ CRP ↑ PCT	↑ ESR ↑ CRP ↑ PCT	↑ ESR ↑ CRP ↑ PCT	100%
Other microbial cause	No	No	No	No	No	No	No	No	0%
CoV-2 PCR	Neg	NA	Neg	Pos	Pos	Neg	Neg	Neg	25%
Prior Cov-2 Exposure	NA	NA	NA	Mother PCR+ 3 weeks prior	NA	PCR+ 4 weeks prior	NA	NA	25%
CoV-2 Serology	+	+	+	+	+	+ Appendictis 4 weeks prior ↑Transaminases	+ Headache Thrombocytosis ↑Transaminases	+ Headache ↑Transaminases Hypertriglyceridemia	100%
Other Clinical Features	Scrotal pain TCP ↑Transaminases RAD	TCP ↑Transaminases RAD	SOB Pleural effusions Thrombocytosis ↑Transaminases	Thrombocytosis ↑Transaminases	SOB Headache Hypertension Pneumonia ↑Transaminases RAD
Treatment	IVIG TCZ x3 enoxaparin ASA	IVIG x2 TCZ x2 enoxaparin ASA	TCZ enoxaparin ASA	IVIG x1 TCZ x2 enoxaparin	IVIG x1 TCZ x1 enoxaparin	IVIG x1 TCZ x2 enoxaparin ASA	IVIG x1 TCZ x1 enoxaparin	IVIG x1 TCZ x1 enoxaparin ASA hydrocortisone
Admission duration (days)	8	6	6	5	3	8	6	5	6
Outcome	Favorable	Favorable	Favorable	Favorable	Favorable	Favorable	Favorable	Favorable	Favorable

Note: All patients are between the ages of 3 – 20