Table 3.
Clinical Outcomes. NEC – Necrotising Enterocolitis; TANEC – Transfusion-Associated NEC (NEC within 48 h of transfusion)
| Group 1 No feeds |
Group 2 Full feeds |
Group 3 Restricted feeds |
p-value | |
|---|---|---|---|---|
| Time to return to full feeds, hours ± SD | 8 ± 35 | 13 ± 46 | 8 ± 32 | 0.88 |
| Feed intolerance, n (%) | 0 | 5 (25%) | 1 (5%) | 0.02* |
| Abdo distension, n (%) | 1 (5%) | 3 (15%) | 2 (10%) | 0.57 |
| Adverse Events, n (%) | 0 | 0 | 1 (5%)** | 0.36 |
| TANEC, n | 0 | 0 | 0 | n/a |
| NEC, n | 0 | 0 | 0 | n/a*** |
| Late onset sepsis, n | 11/19 | 10/18 | 7/17 | n/a*** |
| Mortality, n | 0 | 0 | 0 | n/a*** |
*p < 0.05
**1 infant treated for suspected NEC (managed conservatively; not proven)
***not appropriate to compare rates of long term outcomes as feeding allocation was for one transfusion only