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. 2020 Jul 7;11:1525. doi: 10.3389/fmicb.2020.01525

TABLE 1.

Minimal Inhibitory Concentration (MIC) values for scopoletin, fluconazole, nystatin, and promethazine against C. tropicalis ATCC® 28707 in the presence or absence of sorbitol or ergosterol.

Tested compounds MIC (μg/mL)
BHI BHI + Sorbitol BHI + Ergosterol BHI + Scopoletin BHI + Promethazole
Scopoletin 50 >200 >200
Fluconazole 250 250 62.5* 31.25
Nystatin 25 >100
Promethazine 3.12

The MIC for fluconazole (MIC/4) * in the presence of scopoletin or promethazole is also shown. MIC assay was performed by microtiter broth dilution method. MIC range: 100 to 0.1 μg/mL. BHI: Brain Heart Infusion.