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. 2020 Jul 9;15:4859–4876. doi: 10.2147/IJN.S245170

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© 2020 Quagliariello et al.

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Cell viability in function of the concentration of free CoQ₁₀ or loaded CoQ₁₀ tested alone or combined with Doxorubicin or Trastuzumab at 200 nM for 72h: (A) cardiomyocytes viability treated with Doxorubicin 200 nM, (B) cardiomyocytes viability treated with Trastuzumab, (C) hepatocytes viability treated with Doxorubicin 200 nM, (D) hepatocytes viability treated with Trastuzumab 200 nM. ***p<0.001; **p<0.01; *p<0.05.

Abbreviations: ns, not significant; CoQ₁₀, Coenzyme Q₁₀; CoQ₁₀-NEs, Coenzyme Q₁₀-loaded, nanoemulsions; CoQ₁₀CT-NEs, Coenzyme Q₁₀-loaded, chitosan-coated nanoemulsions; CoQ₁₀-HA-CT NEs, Coenzyme Q₁₀-loaded, hyaluronic acid and chitosan-coated nanoemulsions.