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. 2020 Jul 9;15:4859–4876. doi: 10.2147/IJN.S245170

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© 2020 Quagliariello et al.

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Quantification of MDA production in cardiomyocytes (A) and hepatocytes (B) treated with Doxorubicin or Trastuzumab alone or combined to free or loaded CoQ₁₀ nano-carriers at 0.1% and 1% of oil. ***p<0.001; **p<0.01; *p<0.05.

Abbreviations: ns, not significant; CoQ₁₀, Coenzyme Q₁₀; CoQ₁₀-NEs, Coenzyme Q₁₀-loaded, nanoemulsions; CoQ₁₀CT-NEs, Coenzyme Q₁₀-loaded, chitosan-coated nanoemulsions; CoQ₁₀-HA-CT NEs, Coenzyme Q₁₀-loaded, hyaluronic acid and chitosan-coated nanoemulsions.